STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EP56_09635S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (275 aa)    
Predicted Functional Partners:
EP56_09630
Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
EP56_10595
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.736
EP56_16675
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.728
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.726
EP56_17670
Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.612
EP56_11615
Ring-cleaving dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.522
EP56_13090
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.522
EP56_12680
Mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.498
EP56_09625
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.442
mprF
lysyl-tRNA synthetase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.436
Your Current Organism:
Listeriaceae bacterium FSLA50209
NCBI taxonomy Id: 1497679
Other names: L. bacterium FSL A5-0209, Listeriaceae bacterium FSL A5-0209
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