node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FG94_03307 | FG94_04750 | FG94_03307 | FG94_04750 | Acetolactate synthase, small subunit. | Aminodeoxychorismate synthase, component I. | 0.848 |
FG94_03307 | gltB | FG94_03307 | FG94_01648 | Acetolactate synthase, small subunit. | Glutamate synthase [NADPH] large subunit GltB. | 0.618 |
FG94_03307 | ilvC | FG94_03307 | FG94_03308 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
FG94_03307 | ilvD | FG94_03307 | FG94_04014 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.913 |
FG94_03307 | ilvE | FG94_03307 | FG94_04659 | Acetolactate synthase, small subunit. | Branched-chain-amino-acid aminotransferase IlvE. | 0.833 |
FG94_03307 | ilvI | FG94_03307 | FG94_03306 | Acetolactate synthase, small subunit. | Acetolactate synthase large subunit IlvI. | 0.999 |
FG94_03307 | leuA_1 | FG94_03307 | FG94_00697 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.948 |
FG94_03307 | leuA_2 | FG94_03307 | FG94_03311 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.963 |
FG94_03307 | leuC | FG94_03307 | FG94_03574 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.955 |
FG94_03307 | leuD | FG94_03307 | FG94_03576 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.970 |
FG94_04750 | FG94_03307 | FG94_04750 | FG94_03307 | Aminodeoxychorismate synthase, component I. | Acetolactate synthase, small subunit. | 0.848 |
FG94_04750 | gltB | FG94_04750 | FG94_01648 | Aminodeoxychorismate synthase, component I. | Glutamate synthase [NADPH] large subunit GltB. | 0.617 |
FG94_04750 | ilvC | FG94_04750 | FG94_03308 | Aminodeoxychorismate synthase, component I. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.793 |
FG94_04750 | ilvD | FG94_04750 | FG94_04014 | Aminodeoxychorismate synthase, component I. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.913 |
FG94_04750 | ilvE | FG94_04750 | FG94_04659 | Aminodeoxychorismate synthase, component I. | Branched-chain-amino-acid aminotransferase IlvE. | 0.671 |
FG94_04750 | ilvI | FG94_04750 | FG94_03306 | Aminodeoxychorismate synthase, component I. | Acetolactate synthase large subunit IlvI. | 0.925 |
FG94_04750 | leuA_1 | FG94_04750 | FG94_00697 | Aminodeoxychorismate synthase, component I. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.955 |
FG94_04750 | leuA_2 | FG94_04750 | FG94_03311 | Aminodeoxychorismate synthase, component I. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.955 |
FG94_04750 | leuC | FG94_04750 | FG94_03574 | Aminodeoxychorismate synthase, component I. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.682 |
FG94_04750 | leuD | FG94_04750 | FG94_03576 | Aminodeoxychorismate synthase, component I. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.478 |