node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDX34295.1 | cobC | MPLSOD_20059 | MPLSOD_80028 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Threonine-phosphate decarboxylase. | 0.898 |
CDX34295.1 | cobD | MPLSOD_20059 | MPLSOD_80027 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.907 |
CDX34295.1 | cobO | MPLSOD_20059 | MPLSOD_80026 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.931 |
CDX34295.1 | cobQ | MPLSOD_20059 | MPLSOD_80116 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.908 |
CDX34295.1 | cobS-2 | MPLSOD_20059 | MPLSOD_210045 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.921 |
CDX34295.1 | cobU | MPLSOD_20059 | MPLSOD_80025 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.917 |
cobC | CDX34295.1 | MPLSOD_80028 | MPLSOD_20059 | Threonine-phosphate decarboxylase. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.898 |
cobC | cobD | MPLSOD_80028 | MPLSOD_80027 | Threonine-phosphate decarboxylase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.991 |
cobC | cobO | MPLSOD_80028 | MPLSOD_80026 | Threonine-phosphate decarboxylase. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.961 |
cobC | cobQ | MPLSOD_80028 | MPLSOD_80116 | Threonine-phosphate decarboxylase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.984 |
cobC | cobS-2 | MPLSOD_80028 | MPLSOD_210045 | Threonine-phosphate decarboxylase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.927 |
cobC | cobT-3 | MPLSOD_80028 | MPLSOD_210044 | Threonine-phosphate decarboxylase. | Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.899 |
cobC | cobU | MPLSOD_80028 | MPLSOD_80025 | Threonine-phosphate decarboxylase. | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.979 |
cobC | hisB | MPLSOD_80028 | MPLSOD_30053 | Threonine-phosphate decarboxylase. | Imidazoleglycerol-phosphate dehydratase. | 0.921 |
cobC | hisF | MPLSOD_80028 | MPLSOD_30059 | Threonine-phosphate decarboxylase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.908 |
cobC | hisH | MPLSOD_80028 | MPLSOD_30055 | Threonine-phosphate decarboxylase. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.912 |
cobD | CDX34295.1 | MPLSOD_80027 | MPLSOD_20059 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.907 |
cobD | cobC | MPLSOD_80027 | MPLSOD_80028 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Threonine-phosphate decarboxylase. | 0.991 |
cobD | cobO | MPLSOD_80027 | MPLSOD_80026 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.980 |
cobD | cobQ | MPLSOD_80027 | MPLSOD_80116 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.984 |