node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBH20175.1 | CBH21409.1 | CLOST_0045 | CLOST_1289 | Alanine racemase domain protein. | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.657 |
CBH20175.1 | oraE | CLOST_0045 | CLOST_1290 | Alanine racemase domain protein. | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 0.973 |
CBH20175.1 | oraS | CLOST_0045 | CLOST_1291 | Alanine racemase domain protein. | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | 0.973 |
CBH20175.1 | ord | CLOST_0045 | CLOST_1294 | Alanine racemase domain protein. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.730 |
CBH20175.1 | orr | CLOST_0045 | CLOST_1288 | Alanine racemase domain protein. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.907 |
CBH20175.1 | ortA | CLOST_0045 | CLOST_1293 | Alanine racemase domain protein. | 2-amino-4-ketopentanoate thiolase (AKPT), alpha subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. Belongs to the OrtA family. | 0.692 |
CBH20175.1 | ortB | CLOST_0045 | CLOST_1292 | Alanine racemase domain protein. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.714 |
CBH20696.1 | megL | CLOST_0570 | CLOST_2039 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor; Belongs to the sulfur carrier protein TusA family. | Methionine gamma-lyase. | 0.597 |
CBH20696.1 | ortB | CLOST_0570 | CLOST_1292 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor; Belongs to the sulfur carrier protein TusA family. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.663 |
CBH21409.1 | CBH20175.1 | CLOST_1289 | CLOST_0045 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Alanine racemase domain protein. | 0.657 |
CBH21409.1 | oraE | CLOST_1289 | CLOST_1290 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 0.953 |
CBH21409.1 | oraS | CLOST_1289 | CLOST_1291 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | 0.953 |
CBH21409.1 | ord | CLOST_1289 | CLOST_1294 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.918 |
CBH21409.1 | orr | CLOST_1289 | CLOST_1288 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.932 |
CBH21409.1 | ortA | CLOST_1289 | CLOST_1293 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-amino-4-ketopentanoate thiolase (AKPT), alpha subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. Belongs to the OrtA family. | 0.933 |
CBH21409.1 | ortB | CLOST_1289 | CLOST_1292 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.933 |
CBH22360.1 | megL | CLOST_2242 | CLOST_2039 | Serine acetyltransferase (SAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Methionine gamma-lyase. | 0.540 |
CBH22360.1 | ortB | CLOST_2242 | CLOST_1292 | Serine acetyltransferase (SAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.762 |
megL | CBH20696.1 | CLOST_2039 | CLOST_0570 | Methionine gamma-lyase. | FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor; Belongs to the sulfur carrier protein TusA family. | 0.597 |
megL | CBH22360.1 | CLOST_2039 | CLOST_2242 | Methionine gamma-lyase. | Serine acetyltransferase (SAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.540 |