node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBH21409.1 | oraE | CLOST_1289 | CLOST_1290 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 0.953 |
CBH21409.1 | oraS | CLOST_1289 | CLOST_1291 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | 0.953 |
CBH21409.1 | ord | CLOST_1289 | CLOST_1294 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.918 |
CBH21409.1 | orr | CLOST_1289 | CLOST_1288 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.932 |
CBH21409.1 | ortA | CLOST_1289 | CLOST_1293 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-amino-4-ketopentanoate thiolase (AKPT), alpha subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. Belongs to the OrtA family. | 0.933 |
CBH21409.1 | ortB | CLOST_1289 | CLOST_1292 | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.933 |
kamD | kamE | CLOST_1379 | CLOST_1378 | D-lysine 5,6-aminomutase alpha subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | D-lysine 5,6-aminomutase beta subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | 0.999 |
kamD | ord | CLOST_1379 | CLOST_1294 | D-lysine 5,6-aminomutase alpha subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.916 |
kamE | kamD | CLOST_1378 | CLOST_1379 | D-lysine 5,6-aminomutase beta subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | D-lysine 5,6-aminomutase alpha subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | 0.999 |
kamE | ord | CLOST_1378 | CLOST_1294 | D-lysine 5,6-aminomutase beta subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.932 |
oraE | CBH21409.1 | CLOST_1290 | CLOST_1289 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.953 |
oraE | oraS | CLOST_1290 | CLOST_1291 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | 0.999 |
oraE | ord | CLOST_1290 | CLOST_1294 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.991 |
oraE | orr | CLOST_1290 | CLOST_1288 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.994 |
oraE | ortA | CLOST_1290 | CLOST_1293 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 2-amino-4-ketopentanoate thiolase (AKPT), alpha subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. Belongs to the OrtA family. | 0.934 |
oraE | ortB | CLOST_1290 | CLOST_1292 | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. | 0.939 |
oraS | CBH21409.1 | CLOST_1291 | CLOST_1289 | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.953 |
oraS | oraE | CLOST_1291 | CLOST_1290 | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine. | 0.999 |
oraS | ord | CLOST_1291 | CLOST_1294 | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP). | 0.991 |
oraS | orr | CLOST_1291 | CLOST_1288 | D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine. | Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate. | 0.994 |