STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kamAL-lysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine. (414 aa)    
Predicted Functional Partners:
kamD
D-lysine 5,6-aminomutase alpha subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively.
 
  
 0.989
kamE
D-lysine 5,6-aminomutase beta subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively.
 
  
  0.984
CBH21501.1
Homologs of previously reported genes of unknown function.
 
     0.901
CBH21500.1
Putative MutS-like ATPases involved in mismatch repair, family 2.
 
     0.853
kdd
3,5-diaminohexanoate dehydrogenase; Involved in the anaerobic fermentation of lysine. Catalyzes the oxidative deamination of L-erythro-3,5-diaminohexanoate (3,5-DAH) to 3-keto-5-aminohexanoate (KAH); Belongs to the KDD family.
 
   
 0.816
cheR
CheR.
    
   0.808
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.805
kal
3-aminobutyryl-CoA ammonia lyase; Involved in the anaerobic fermentation of lysine. Catalyzes the deamination of L-3-aminobutyryl-CoA to produce crotonoyl-CoA. Belongs to the KAL family.
 
     0.673
kce
3-keto-5-aminohexanoate cleavage enzyme; Involved in the anaerobic fermentation of lysine. Catalyzes the reversible reaction between 3-keto-5-aminohexanoate (KAH) and acetyl-CoA to form 3-aminobutyryl-CoA and acetoacetate. The reaction involves the deprotonation of KAH, the nucleophilic addition onto acetyl-CoA and the intramolecular transfer of the CoA moiety. Belongs to the KCE family.
     
 0.481
yhdR
Putative aspartate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.479
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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