STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdAD-proline reductase proprotein PrdA; D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group. (629 aa)    
Predicted Functional Partners:
pdrB
D-proline reductase gamma chain; D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group.
  
 0.998
prdF
Proline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the proline racemase family.
 
  
 0.991
prdC
Electron transfer protein; Function of homologous gene experimentally demonstrated in an other organism; putative carrier.
 
   
 0.949
CBH22352.1
Homologs of previously reported genes of unknown function.
 
     0.934
ord
(2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP).
     
  0.900
CBH22347.1
Conserved membrane protein of unknown function (PrdG); Homologs of previously reported genes of unknown function.
 
     0.870
CBH20522.1
Proton-dependent oligopeptide transporter precursor.
  
     0.745
CBH22350.1
Putative uncharacterized protein (PrdD); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
0.642
CBH22349.1
Putative uncharacterized protein (PrdE); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    
0.602
prdR
Sigma-54-dependent transcriptional activator; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.592
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
Server load: medium (74%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.