STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmCFAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (669 aa)    
Predicted Functional Partners:
ALQ56480.1
Hypothetical protein; Pfam:pfam04273 Putative phosphatase (DUF442).
  
 0.891
sqr
NAD(FAD)-dependent dehydrogenase; Pfam:pfam04273 Putative phosphatase (DUF442).
  
 0.891
ALQ53880.1
Hypothetical protein.
  
 
 0.787
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.787
fabB
Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
 0.759
gltB
Pfam:pfam01645 Conserved region in glutamate synthase.
  
  
 0.713
rlmL
Ribosomal RNA large subunit methyltransferase K/L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
  
 0.682
glpA
Glycerol-3-phosphate dehydrogenase; Pfam:pfam01266 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.579
thiDE
Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.564
gpsA
Pfam:pfam07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.557
Your Current Organism:
Pseudoalteromonas issachenkonii
NCBI taxonomy Id: 152297
Other names: CIP 106858, DSM 15925, KCTC 12958, KMM 3549, LMG 19697, LMG:19697, P. issachenkonii, Pseudoalteromonas issachenkonii Ivanova et al. 2002, Pseudoalteromonas sp. F13, Pseudoalteromonas sp. F2, Pseudoalteromonas sp. KMM 3549
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