node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dml | Ena | SAMN04488579_1126 | SAMN04488579_11211 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.633 |
Dml | Hnr | SAMN04488579_1126 | SAMN04488579_11219 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate. | 0.572 |
Dml | MgmL | SAMN04488579_1126 | SAMN04488579_1127 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Conserved hypothetical protein. | 0.833 |
Dml | SDX31168.1 | SAMN04488579_1126 | SAMN04488579_101114 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.823 |
Dml | SDX95577.1 | SAMN04488579_1126 | SAMN04488579_1125 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | L-serine dehydratase. | 0.905 |
Dml | SDX95753.1 | SAMN04488579_1126 | SAMN04488579_11210 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Amino acid synthesis. | 0.694 |
Dml | SDY07782.1 | SAMN04488579_1126 | SAMN04488579_11561 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. | 0.457 |
Dml | SDY18162.1 | SAMN04488579_1126 | SAMN04488579_1198 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.823 |
Dml | mgm | SAMN04488579_1126 | SAMN04488579_1129 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | methylmalonyl-CoA mutase C-terminal domain-containing protein; Involved in the fermentation of nicotinate to ammonia, propionate, acetate and carbon dioxide. | 0.856 |
Dml | mii | SAMN04488579_1126 | SAMN04488579_1128 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | Methylitaconate delta2-delta3-isomerase; Catalyzes the reversible isomerization of (R)-3- methylitaconate to 2,3-dimethylmaleate. Has very low isomerase activity with itaconate. | 0.967 |
Ena | Dml | SAMN04488579_11211 | SAMN04488579_1126 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | 0.633 |
Ena | Hnr | SAMN04488579_11211 | SAMN04488579_11219 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate. | 0.974 |
Ena | MgmL | SAMN04488579_11211 | SAMN04488579_1127 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Conserved hypothetical protein. | 0.760 |
Ena | SDX95577.1 | SAMN04488579_11211 | SAMN04488579_1125 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | L-serine dehydratase. | 0.868 |
Ena | SDX95753.1 | SAMN04488579_11211 | SAMN04488579_11210 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Amino acid synthesis. | 0.935 |
Ena | mgm | SAMN04488579_11211 | SAMN04488579_1129 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | methylmalonyl-CoA mutase C-terminal domain-containing protein; Involved in the fermentation of nicotinate to ammonia, propionate, acetate and carbon dioxide. | 0.853 |
Ena | mii | SAMN04488579_11211 | SAMN04488579_1128 | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Methylitaconate delta2-delta3-isomerase; Catalyzes the reversible isomerization of (R)-3- methylitaconate to 2,3-dimethylmaleate. Has very low isomerase activity with itaconate. | 0.644 |
Hnr | Dml | SAMN04488579_11219 | SAMN04488579_1126 | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate. | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate. | 0.572 |
Hnr | Ena | SAMN04488579_11219 | SAMN04488579_11211 | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate. | Enamidase; Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.974 |
Hnr | MgmL | SAMN04488579_11219 | SAMN04488579_1127 | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate. | Conserved hypothetical protein. | 0.706 |