STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdsAannotation not available (249 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family
 
 0.950
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Corresponds to locus_tag Z4372; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
 
 
 0.939
rseP
Regulator of sigma E protease; A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA. This provides the cell with sigma- E (RpoE) activity through the proteolysis of RseA (By similarity); Belongs to the peptidase M50B family
 
    0.930
pssA
Phosphatidylserine synthase phospholipid synthesis; Corresponds to locus_tag Z3870
  
 
 0.926
Z1139
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid
    
 0.906
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid
    
 0.906
Z2318
Phosphatidate cytidylyltransferase; Corresponds to locus_tag Z2318; Belongs to the CDS family
 
  
 
0.825
bamA
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery
  
    0.809
cdh
CDP-diacylglycerol pyrophosphatase; Corresponds to locus_tag Z5463
     
  0.800
uppS
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide
  
  
 0.775
Your Current Organism:
Escherichia coli O157H7
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933, Escherichia coli O157H7
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