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speG protein (Escherichia coli O157H7) - STRING interaction network
"speG" - Spermidine N(1)-acetyltransferase in Escherichia coli O157H7
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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speGSpermidine N(1)-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine; Belongs to the acetyltransferase family (186 aa)    
Predicted Functional Partners:
ynfB
UPF0482 protein YnfB; Corresponds to locus_tag Z2570; Belongs to the UPF0482 family (113 aa)
   
   
  0.965
speC
Ornithine decarboxylase isozyme; Corresponds to locus_tag Z4310 (711 aa)
         
  0.955
speE
Polyamine aminopropyltransferase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine (288 aa)
         
  0.946
Z2491
Putative glutamine synthetase; Corresponds to locus_tag Z2491; Belongs to the glutamine synthetase family (472 aa)
       
  0.929
patA
Putrescine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine (459 aa)
       
  0.912
ECs0721
Ornithine decarboxylase isozyme; Corresponds to locus_tag Z0839 (735 aa)
         
  0.906
speB
Agmatinase; Catalyzes the formation of putrescine from agmatine; Belongs to the arginase family. Agmatinase subfamily (306 aa)
         
  0.903
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (951 aa)
         
  0.645
dtpA
Dipeptide and tripeptide permease A; Proton-dependent permease that transports di- and tripeptides (500 aa)
       
 
  0.643
der
GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis (490 aa)
     
   
  0.639
Your Current Organism:
Escherichia coli O157H7
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933, Escherichia coli O157H7
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