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gne protein (Escherichia coli O157H7) - STRING interaction network
"gne" - N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase in Escherichia coli O157H7
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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gneN-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase; Involved in biosynthesis of the repeating tetrasaccharide unit of the O-antigen. Catalyzes the reversible epimerization of the hydroxyl group at position C4 of undecaprenyl pyrophosphate-N-acetylglucosamine (UndPP-GlcNAc) to yield undecaprenyl pyrophosphate-N-acetylgalactosamine (UndPP-GalNAc) (331 aa)    
Predicted Functional Partners:
galU
UTP--glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family (302 aa)
       
  0.915
galT
Galactose-1-phosphate uridylyltransferase; Corresponds to locus_tag Z0928; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family (348 aa)
         
  0.907
galF
UTP--glucose-1-phosphate uridylyltransferase; Corresponds to locus_tag Z3205 (297 aa)
         
  0.799
ECs2848
Uncharacterized protein; Corresponds to locus_tag Z3207 (464 aa)
         
  0.742
wcaL
Putative colanic acid biosynthesis glycosyl transferase; Corresponds to locus_tag Z3208 (406 aa)
   
 
  0.636
wzzE
ECA polysaccharide chain length modulation protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) (348 aa)
         
  0.621
torR
TorCAD operon transcriptional regulatory protein TorR; Member of the two-component regulatory system TorS/TorR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Phosphorylated TorR activates the transcription of the torCAD operon by binding to four decameric boxes located in the torCAD promoter. Box1, 2 and 4 contain the DNA sequence 5’- CTGTTCATAT-3’ and box3 contains the DNA sequence 5’-CCGTTCATCC-3’. Phosphorylated as well as unphosphorylated TorR negatively regulates its own expression by binding to box1 and 2 (By similarity) (230 aa)
           
  0.620
wbdN
Putative glycosyl transferase; Corresponds to locus_tag Z3204 (260 aa)
   
 
  0.615
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations (484 aa)
         
  0.605
Z3203
O antigen polymerase; Corresponds to locus_tag Z3203 (394 aa)
         
  0.599
Your Current Organism:
Escherichia coli O157H7
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933, Escherichia coli O157H7
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