STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hycIHydrogenase 3 maturation protease; Protease involved in the C-terminal processing of HycE, the large subunit of hydrogenase 3 (156 aa)    
Predicted Functional Partners:
ECs3577
Hydrogenase 3 large subunit; Corresponds to locus_tag Z4029
 
  
 0.992
ECs3578
Membrane-spanning protein of hydrogenase 3; Corresponds to locus_tag Z4030
 
  
 0.990
hycH
Formate hydrogenlyase maturation protein HycH; Seems to be required for the conversion of a precursor form of the large subunit of hydrogenlyase (HycE) into a mature form
    0.983
hycG
Formate hydrogenlyase subunit-7 component G; Corresponds to locus_tag Z4027
 
  
 0.980
hycF
Probable iron-sulfur protein of hydrogenase 3 (Part of FHL complex); Corresponds to locus_tag Z4028; Formate hydrogenlyase subunit 6; Ni,Fe-hydrogenase III medium subunit
 
  
 0.966
hycB
Formate hydrogenlyase subunit-7 component B; Corresponds to locus_tag Z4032
 
  
 0.960
ECs3579
Membrane-spanning protein of hydrogenase 3; Corresponds to locus_tag Z4031
 
    0.957
hyfG
Hydrogenase 4 subunit; Corresponds to locus_tag Z3747
 
  
 0.879
Z3750
Uncharacterized protein; Corresponds to locus_tag Z3750
    0.869
hycA
Formate hydrogenlyase regulatory protein HycA; Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with FhlA or by preventing the binding of FhlA to the upstream activatory sequence (By similarity)
 
  
 0.864
Your Current Organism:
Escherichia coli O157H7
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933, Escherichia coli O157H7
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