STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlyBAlpha-hemolysin translocation ATP-binding protein HlyB; Part of the ABC transporter complex HlyBD involved in hemolysin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) (706 aa)    
Predicted Functional Partners:
hlyD
annotation not available
  
 0.996
hlyA
annotation not available
  
 0.958
hlyC
annotation not available
     
 0.887
Z0635
Putative membrane fusion protein of a transport system; Corresponds to locus_tag Z0635
  
 0.765
Z0608
Putative outer membrane transport protein; Corresponds to locus_tag Z0608
  
  
 0.710
AIG66770.1
Corresponds to locus_tag Z0615
  
  
 0.684
macA
Macrolide export protein MacA; Part of the tripartite efflux system MacAB-TolC. MacA stimulates the ATPase activity of MacB by promoting the closed ATP-bound state of MacB, increases the capacity of MacB to bind macrolides such as erythromycin, and provides a physical link between MacB and TolC. Confers resistance against macrolides (By similarity)
  
  
 0.663
AIG71932.1
annotation not available
       0.636
repFIB
annotation not available
      
 0.621
Z0510
Toxin; Corresponds to locus_tag Z0510; Belongs to the RelE toxin family
      
 0.487
Your Current Organism:
Escherichia coli O157H7
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933, Escherichia coli O157H7
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