STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribFPutative regulator; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. (313 aa)    
Predicted Functional Partners:
ribE
Riboflavin synthase, alpha chain; Residues 1 to 213 of 213 are 99.53 pct identical to residues 1 to 213 of 213 from Escherichia coli K-12 Strain MG1655: B1662.
  
 
 0.964
ycbP
Orf, hypothetical protein; Residues 1 to 191 of 191 are 97.38 pct identical to residues 1 to 191 of 191 from Escherichia coli K-12 Strain MG1655: B0937.
    
 0.910
yigB
Putative phosphatase; Residues 1 to 238 of 238 are 99.15 pct identical to residues 1 to 238 of 238 from Escherichia coli K-12 Strain MG1655: B3812.
  
 
 0.910
ybjI
Orf, hypothetical protein; Residues 1 to 262 of 262 are 98.09 pct identical to residues 1 to 262 of 262 from Escherichia coli K-12 Strain MG1655: B0844.
   
 0.909
ubiB
Ferrisiderophore reductase; Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides; Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
    
  0.908
ribH
Hypothetical protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
  
 0.905
appA
Phosphoanhydride phosphorylase; Residues 11 to 444 of 444 are 98.15 pct identical to residues 1 to 432 of 432 from Escherichia coli K-12 Strain MG1655: B0980.
     
  0.900
aphA
Diadenosine tetraphosphatase; Residues 1 to 237 of 237 are 99.15 pct identical to residues 1 to 237 of 237 from Escherichia coli K-12 Strain MG1655: B4055; Belongs to the class B bacterial acid phosphatase family.
     
  0.900
Z0028
Orf, hypothetical protein; Residues 1 to 74 of 74 are 94.59 pct identical to residues 1 to 72 of 72 from Escherichia coli K-12 Strain MG1655: B0024.
     
 0.847
ribD
Bifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.817
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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