STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase (decarboxylase component); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)    
Predicted Functional Partners:
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
lpdA
Lipoamide dehydrogenase (NADH); Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.999
ydbK
Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378.
     
 0.965
maeB
Putative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463.
  
 
 0.948
ldhA
Fermentative D-lactate dehydrogenase, NAD-dependent; Residues 1 to 329 of 329 are 99.69 pct identical to residues 1 to 329 of 329 from Escherichia coli K-12 Strain MG1655: B1380; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.945
pykA
Pyruvate kinase II, glucose stimulated; Residues 1 to 480 of 480 are 99.58 pct identical to residues 1 to 480 of 480 from Escherichia coli K-12 Strain MG1655: B1854; Belongs to the pyruvate kinase family.
  
 
 0.937
dld
D-lactate dehydrogenase, FAD protein, NADH independent; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
     
 0.936
pflD
Formate acetyltransferase 2; Residues 1 to 765 of 765 are 98.82 pct identical to residues 1 to 765 of 765 from Escherichia coli K-12 Strain MG1655: B3951.
     
 0.922
pykF
Pyruvate kinase I (formerly F), fructose stimulated; Residues 1 to 470 of 470 are 100.00 pct identical to residues 1 to 470 of 470 from Escherichia coli K-12 Strain MG1655: B1676.
  
 
 0.920
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.916
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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