STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdsACDP-diglyceride synthetase; Residues 1 to 249 of 249 are 100.00 pct identical to residues 1 to 249 of 249 from Escherichia coli K-12 Strain MG1655: B0175. (249 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.982
yaeS
Orf, hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
 
  
 0.965
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Residues 1 to 245 of 245 are 99.59 pct identical to residues 1 to 245 of 245 from Escherichia coli K-12 Strain MG1655: B3018; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    
 0.962
pssA
Phosphatidylserine synthase; Residues 1 to 452 of 452 are 100.00 pct identical to residues 1 to 452 of 452 from Escherichia coli K-12 Strain MG1655: B2585.
     
 0.961
ynbB
Putative phosphatidate cytidiltransferase; Residues 1 to 298 of 298 are 94.63 pct identical to residues 1 to 298 of 298 from Escherichia coli K-12 Strain MG1655: B1409; Belongs to the CDS family.
  
  
 
0.918
Z1139
Putative diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
    
 0.908
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
    
 0.908
cdh
CDP-diacylglycerol phosphotidylhydrolase; Residues 1 to 251 of 251 are 98.80 pct identical to residues 1 to 251 of 251 from Escherichia coli K-12 Strain MG1655: B3918.
     
 0.900
yaeL
Orf, hypothetical protein; A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA. This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA (By similarity); Belongs to the peptidase M50B family.
  
  
 0.888
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
     
 0.792
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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