STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybaRPutative ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). (834 aa)    
Predicted Functional Partners:
sodC_1
Putative copper-zinc superoxide dismutase encoded within prophage CP-933R; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.953
sodC
Superoxide dismutase precursor (Cu-Zn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
   
 0.953
Z3312
Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.953
zntA
Zinc-transporting ATPase; Residues 1 to 732 of 732 are 98.90 pct identical to residues 1 to 732 of 732 from Escherichia coli K-12 Strain MG1655: B3469.
 
 
0.852
ydbK
Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378.
  
  
 0.810
yacK
Orf, hypothetical protein; Probably involved in periplasmic detoxification of copper by oxidizing Cu(+) to Cu(2+) and thus preventing its uptake into the cytoplasm. Possesses phenoloxidase and ferroxidase activities and might be involved in the production of polyphenolic compounds and the prevention of oxidative damage in the periplasm (By similarity).
  
 
 0.739
ybgR
Putative transport system permease protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
  
  
 0.677
arsR
Transcriptional repressor of chromosomal ars operon; Residues 1 to 117 of 117 are 94.87 pct identical to residues 1 to 117 of 117 from Escherichia coli K-12 Strain MG1655: B3501.
 
  
 0.660
ybbI
Putative transcriptional regulator; Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity).
  
  
 0.654
yaiN
Putative alpha helix chain; Repressor of the frmRAB operon; Belongs to the FrmR/RcnR family.
  
  
 0.647
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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