STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybbTOrf, hypothetical protein; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate. (160 aa)    
Predicted Functional Partners:
ylbC
Putative malate dehydrogenase; AllD plays a pivotal role as a metabolic branch-point enzyme in nitrogen utilization via the assimilation of allantoin. It is able to utilize allantoin as a sole source of nitrogen under anaerobic conditions. Catalyzes the oxidation of ureidoglycolate to oxalurate. Belongs to the LDH2/MDH2 oxidoreductase family.
     
 0.979
gcl
Glyoxylate carboligase; Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). Belongs to the TPP enzyme family.
 
  
 0.970
ylbA
Orf, hypothetical protein; Residues 1 to 261 of 261 are 99.23 pct identical to residues 1 to 261 of 261 from Escherichia coli K-12 Strain MG1655: B0515.
 
  
  0.925
aceB
Malate synthase A; Residues 1 to 533 of 533 are 99.62 pct identical to residues 1 to 533 of 533 from Escherichia coli K-12 Strain MG1655: B4014; Belongs to the malate synthase family.
    
 0.911
ureA
Putative urease structural subunit A (gamma); Residues 1 to 100 of 100 are 95.99 pct identical to residues 1 to 100 of 100 from GenPept 118 : gi|149336|gb|AAA25149.1| (M36068) urease subunit A [Klebsiella aerogenes]; Belongs to the urease gamma subunit family.
    
  0.901
ureB
Putative urease structural subunit B (beta); Residues 1 to 106 of 106 are 82.07 pct identical to residues 1 to 106 of 106 from GenPept 118 : gi|149337|gb|AAA25150.1| (M36068) urease subunit B [Klebsiella aerogenes]; Belongs to the urease beta subunit family.
    
  0.901
ureC
Putative urease structural subunit C (alpha); Residues 2 to 568 of 568 are 90.82 pct identical to residues 1 to 567 of 567 from GenPept 118 : gi|149338|gb|AAA25151.1| (M36068) urease subunit C [Klebsiella aerogenes]; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
    
  0.901
aceA
Isocitrate lyase; Residues 6 to 439 of 439 are 99.53 pct identical to residues 1 to 434 of 434 from Escherichia coli K-12 Strain MG1655: B4015.
     
 0.887
ybbQ
Putative oxidoreductase; Residues 1 to 292 of 292 are 98.97 pct identical to residues 1 to 292 of 292 from Escherichia coli K-12 Strain MG1655: B0509.
  
  
 0.801
ycdW
Putative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
     
  0.800
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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