STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybdUOrf, hypothetical protein; Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein; Belongs to the CitX family. (183 aa)    
Predicted Functional Partners:
citG
Orf, hypothetical protein; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family.
 
 0.999
citF
Citrate lyase alpha chain; Residues 1 to 510 of 510 are 99.41 pct identical to residues 1 to 510 of 510 from Escherichia coli K-12 Strain MG1655: B0615.
 
  
 0.997
citD
Citrate lyase acyl carrier protein (gamma chain); Covalent carrier of the coenzyme of citrate lyase.
 
  
 0.997
citC
Citrate lyase synthetase (citrate (pro-3S)-lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
 
 0.992
citE
Citrate lyase beta chain (acyl lyase subunit); Residues 1 to 307 of 307 are 99.34 pct identical to residues 1 to 307 of 307 from Escherichia coli K-12 Strain MG1655: B0616; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.985
ybdS
Putative a membrane protein; Responsible for the uptake of citrate in exchange to the efflux of succinate. Has a relatively broad specificity for C(4)- dicarboxylates and tricarboxylates (By similarity); Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
 
  
 0.925
Z1166
Hypothetical protein; Residues 5 to 309 of 318 are 42.39 pct identical to residues 9 to 308 of 310 from GenPept 118 : gi|6460023|gb|AAF11768.1|AE002054_13 (AE002054) hypothetical protein [Deinococcus radiodurans].
  
  
 0.670
Z1605
Hypothetical protein; Residues 5 to 309 of 318 are 42.39 pct identical to residues 9 to 308 of 310 from GenPept 118 : gi|6460023|gb|AAF11768.1|AE002054_13 (AE002054) hypothetical protein [Deinococcus radiodurans].
  
  
 0.670
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
   
    0.627
nanA
N-acetylneuraminate lyase (aldolase); Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
   
    0.627
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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