node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceF | gltB | Z0125 | Z4576 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | 0.642 |
aceF | lpdA | Z0125 | Z0126 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoamide dehydrogenase (NADH); Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.999 |
aceF | sdhA | Z0125 | Z0877 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.606 |
aceF | sdhB | Z0125 | Z0878 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, iron sulfur protein; Residues 1 to 238 of 238 are 99.57 pct identical to residues 1 to 238 of 238 from Escherichia coli K-12 Strain MG1655: B0724; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.592 |
aceF | sdhC | Z0125 | Z0875 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556; Membrane-anchoring subunit of succinate dehydrogenase (SDH). Belongs to the cytochrome b560 family. | 0.448 |
aceF | sucA | Z0125 | Z0880 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase (decarboxylase component); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.977 |
aceF | sucC | Z0125 | Z0882 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.947 |
aceF | sucD | Z0125 | Z0883 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.923 |
gltB | aceF | Z4576 | Z0125 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.642 |
gltB | icdA | Z4576 | Z1865 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | Isocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136. | 0.971 |
gltB | lpdA | Z4576 | Z0126 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | Lipoamide dehydrogenase (NADH); Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.900 |
gltB | sdhA | Z4576 | Z0877 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | Succinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.672 |
gltB | sdhC | Z4576 | Z0875 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | Succinate dehydrogenase, cytochrome b556; Membrane-anchoring subunit of succinate dehydrogenase (SDH). Belongs to the cytochrome b560 family. | 0.649 |
gltB | sucA | Z4576 | Z0880 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | 2-oxoglutarate dehydrogenase (decarboxylase component); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.959 |
gltB | sucB | Z4576 | Z0881 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | 2-oxoglutarate dehydrogenase (dihydrolipoyltranssuccinase E2 component); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.642 |
gltB | sucC | Z4576 | Z0882 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.791 |
gltB | sucD | Z4576 | Z0883 | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.498 |
icdA | gltB | Z1865 | Z4576 | Isocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136. | Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212. | 0.971 |
icdA | lpdA | Z1865 | Z0126 | Isocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136. | Lipoamide dehydrogenase (NADH); Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.749 |
icdA | sdhA | Z1865 | Z0877 | Isocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136. | Succinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.660 |