STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhEPutative isomerase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.941
gnd
Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
  
 0.936
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
     
 0.905
gntK
Gluconokinase 2, thermoresistant; Residues 1 to 162 of 162 are 100.00 pct identical to residues 1 to 162 of 162 from Escherichia coli K-12 Strain MG1655: B3437.
     
 0.900
yebY
Orf, hypothetical protein; Residues 1 to 113 of 113 are 98.23 pct identical to residues 1 to 113 of 113 from Escherichia coli K-12 Strain MG1655: B1839.
  
     0.618
ybhA
Putative phosphatase; Residues 1 to 272 of 272 are 99.26 pct identical to residues 1 to 272 of 272 from Escherichia coli K-12 Strain MG1655: B0766.
       0.525
yqjK
Orf, hypothetical protein; Residues 1 to 99 of 99 are 98.98 pct identical to residues 1 to 99 of 99 from Escherichia coli K-12 Strain MG1655: B3100.
  
     0.437
sseB
Enhanced serine sensitivity; Residues 51 to 269 of 269 are 99.08 pct identical to residues 43 to 261 of 261 from Escherichia coli K-12 Strain MG1655: B2522.
  
     0.424
hha
Haemolysin expression modulating protein; Down-regulates hemolysin expression, in complex with H-NS, and can also stimulate transposition events in vivo. Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes DNA bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex. Binds DNA and influences DNA topology in response to environmental stimuli. Decreases biofilm formation (By similarity); Belongs to the Hha/YmoA/Cnu family.
  
     0.412
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.