STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aatLeucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (234 aa)    
Predicted Functional Partners:
yljA
Orf, hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
 
  
 0.861
cydC
ATP-binding component of cytochrome-related transport; Residues 1 to 573 of 573 are 98.95 pct identical to residues 1 to 573 of 573 from Escherichia coli K-12 Strain MG1655: B0886.
       0.672
cydD
ATP-binding component of cytochrome-related transport, Zn sensitive; Residues 1 to 588 of 588 are 99.31 pct identical to residues 1 to 588 of 588 from Escherichia coli K-12 Strain MG1655: B0887.
       0.671
yafK
Orf, hypothetical protein; Residues 1 to 246 of 246 are 100.00 pct identical to residues 1 to 246 of 246 from Escherichia coli K-12 Strain MG1655: B0224.
      
 0.558
infA
Protein chain initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
     
 0.534
trxB
Thioredoxin reductase; Residues 1 to 321 of 321 are 100.00 pct identical to residues 1 to 321 of 321 from Escherichia coli K-12 Strain MG1655: B0888.
       0.474
clpA
ATP-binding component of serine protease; ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins (By similarity). Belongs to the ClpA/ClpB family.
 
  
 0.448
tolC
Outer membrane channel; Residues 1 to 495 of 495 are 99.79 pct identical to residues 1 to 495 of 495 from Escherichia coli K-12 Strain MG1655: B3035.
      
 0.433
tyrA
Chorismate mutase-T and prephenate dehydrogenase; Residues 1 to 373 of 373 are 99.46 pct identical to residues 1 to 373 of 373 from Escherichia coli K-12 Strain MG1655: B2600.
 
   
 0.432
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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