node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Z1045 | Z1046 | Z1045 | Z1046 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Hypothetical protein; Residues 1 to 178 of 184 are 100.00 pct identical to residues 1 to 178 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | 0.989 |
Z1045 | adhE | Z1045 | Z2016 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | 0.941 |
Z1045 | mhpF | Z1045 | Z0450 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.900 |
Z1045 | pflA | Z1045 | Z1246 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.814 |
Z1045 | pflB | Z1045 | Z1248 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Formate acetyltransferase 1; Residues 1 to 760 of 760 are 99.47 pct identical to residues 1 to 760 of 760 from Escherichia coli K-12 Strain MG1655: B0903. | 0.921 |
Z1045 | pflD | Z1045 | Z5507 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Formate acetyltransferase 2; Residues 1 to 765 of 765 are 98.82 pct identical to residues 1 to 765 of 765 from Escherichia coli K-12 Strain MG1655: B3951. | 0.917 |
Z1045 | tdcE | Z1045 | Z4466 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Probable formate acetyltransferase 3; Residues 1 to 741 of 764 are 99.86 pct identical to residues 1 to 741 of 746 from Escherichia coli K-12 Strain MG1655: B3114. | 0.921 |
Z1045 | ydbK | Z1045 | Z2332 | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378. | 0.970 |
Z1046 | Z1045 | Z1046 | Z1045 | Hypothetical protein; Residues 1 to 178 of 184 are 100.00 pct identical to residues 1 to 178 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | 0.989 |
Z1046 | pflA | Z1046 | Z1246 | Hypothetical protein; Residues 1 to 178 of 184 are 100.00 pct identical to residues 1 to 178 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.444 |
Z1046 | ydbK | Z1046 | Z2332 | Hypothetical protein; Residues 1 to 178 of 184 are 100.00 pct identical to residues 1 to 178 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378. | 0.712 |
adhE | Z1045 | Z2016 | Z1045 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | 0.941 |
adhE | mhpF | Z2016 | Z0450 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.980 |
adhE | pflA | Z2016 | Z1246 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.708 |
adhE | pflB | Z2016 | Z1248 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Formate acetyltransferase 1; Residues 1 to 760 of 760 are 99.47 pct identical to residues 1 to 760 of 760 from Escherichia coli K-12 Strain MG1655: B0903. | 0.992 |
adhE | pflD | Z2016 | Z5507 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Formate acetyltransferase 2; Residues 1 to 765 of 765 are 98.82 pct identical to residues 1 to 765 of 765 from Escherichia coli K-12 Strain MG1655: B3951. | 0.941 |
adhE | tdcE | Z2016 | Z4466 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Probable formate acetyltransferase 3; Residues 1 to 741 of 764 are 99.86 pct identical to residues 1 to 741 of 746 from Escherichia coli K-12 Strain MG1655: B3114. | 0.989 |
adhE | ydbK | Z2016 | Z2332 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378. | 0.994 |
adhE | yfiD | Z2016 | Z3862 | CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family. | Putative formate acetyltransferase; Acts as a radical domain for damaged PFL and possibly other radical proteins. | 0.521 |
mhpF | Z1045 | Z0450 | Z1045 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Putative pyruvate formate-lyase 2; Residues 1 to 599 of 599 are 98.66 pct identical to residues 212 to 810 of 810 from Escherichia coli K-12 Strain MG1655: B0823. | 0.900 |