node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
asnS | pncB | Z1278 | Z1279 | Asparagine tRNA synthetase; Residues 1 to 466 of 466 are 99.57 pct identical to residues 1 to 466 of 466 from Escherichia coli K-12 Strain MG1655: B0930. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.912 |
deoD | nadR | Z5986 | Z5991 | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | Probable nadAB transcriptional regulator; Residues 1 to 417 of 417 are 99.52 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B4390. | 0.915 |
deoD | pncB | Z5986 | Z1279 | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.912 |
deoD | ydjB | Z5986 | Z2802 | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | Orf, hypothetical protein; Residues 1 to 219 of 219 are 99.08 pct identical to residues 1 to 219 of 219 from Escherichia coli K-12 Strain MG1655: B1768. | 0.900 |
deoD | yjjG | Z5986 | Z5975 | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | Putative phosphatase; Nucleotidase that shows high phosphatase activity toward non- canonical pyrimidine nucleotides and three canonical nucleoside 5'- monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate. Appears to function as a house-cleaning nucleotidase in vivo, since the general nucleotidase activity of YjjG allows it to protect cells against non- canonical pyrimidine derivatives such as 5-fluoro-2'-deoxyuridine, 5- fluorouridine, 5-fluoroorotate, 5-fluorouracil, and 5-aza-2'- deoxycytidine, and prevents t [...] | 0.915 |
mazG | nadC | Z4096 | Z0119 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | 0.902 |
mazG | nadR | Z4096 | Z5991 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Probable nadAB transcriptional regulator; Residues 1 to 417 of 417 are 99.52 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B4390. | 0.913 |
mazG | pncB | Z4096 | Z1279 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.915 |
mazG | ybeN | Z4096 | Z0786 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Orf, hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.902 |
mazG | ygaD | Z4096 | Z4003 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Orf, hypothetical protein; Residues 1 to 165 of 165 are 99.39 pct identical to residues 1 to 165 of 165 from Escherichia coli K-12 Strain MG1655: B2700; Belongs to the CinA family. | 0.911 |
mazG | yjaD | Z4096 | Z5571 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Orf, hypothetical protein; Residues 1 to 257 of 257 are 98.44 pct identical to residues 1 to 257 of 257 from Escherichia coli K-12 Strain MG1655: B3996. | 0.910 |
mazG | yjjG | Z4096 | Z5975 | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | Putative phosphatase; Nucleotidase that shows high phosphatase activity toward non- canonical pyrimidine nucleotides and three canonical nucleoside 5'- monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate. Appears to function as a house-cleaning nucleotidase in vivo, since the general nucleotidase activity of YjjG allows it to protect cells against non- canonical pyrimidine derivatives such as 5-fluoro-2'-deoxyuridine, 5- fluorouridine, 5-fluoroorotate, 5-fluorouracil, and 5-aza-2'- deoxycytidine, and prevents t [...] | 0.900 |
nadC | mazG | Z0119 | Z4096 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Orf, hypothetical protein; Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin- antitoxin (TA) system that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA (By similarity); Belongs to the nucleoside triphosphate py [...] | 0.902 |
nadC | nadR | Z0119 | Z5991 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Probable nadAB transcriptional regulator; Residues 1 to 417 of 417 are 99.52 pct identical to residues 1 to 417 of 417 from Escherichia coli K-12 Strain MG1655: B4390. | 0.956 |
nadC | pncB | Z0119 | Z1279 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.983 |
nadC | ybeN | Z0119 | Z0786 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Orf, hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.980 |
nadC | ydjB | Z0119 | Z2802 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Orf, hypothetical protein; Residues 1 to 219 of 219 are 99.08 pct identical to residues 1 to 219 of 219 from Escherichia coli K-12 Strain MG1655: B1768. | 0.653 |
nadC | ygaD | Z0119 | Z4003 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Orf, hypothetical protein; Residues 1 to 165 of 165 are 99.39 pct identical to residues 1 to 165 of 165 from Escherichia coli K-12 Strain MG1655: B2700; Belongs to the CinA family. | 0.958 |
nadC | yjaD | Z0119 | Z5571 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Orf, hypothetical protein; Residues 1 to 257 of 257 are 98.44 pct identical to residues 1 to 257 of 257 from Escherichia coli K-12 Strain MG1655: B3996. | 0.900 |
nadC | yjjG | Z0119 | Z5975 | Quinolinate phosphoribosyltransferase; Residues 1 to 297 of 297 are 99.66 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B0109; Belongs to the NadC/ModD family. | Putative phosphatase; Nucleotidase that shows high phosphatase activity toward non- canonical pyrimidine nucleotides and three canonical nucleoside 5'- monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate. Appears to function as a house-cleaning nucleotidase in vivo, since the general nucleotidase activity of YjjG allows it to protect cells against non- canonical pyrimidine derivatives such as 5-fluoro-2'-deoxyuridine, 5- fluorouridine, 5-fluoroorotate, 5-fluorouracil, and 5-aza-2'- deoxycytidine, and prevents t [...] | 0.900 |