node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arnA | arnC | Z3513 | Z3512 | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. | Putative sugar transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.998 |
arnA | yceE | Z3513 | Z1688 | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.532 |
arnA | yjcP | Z3513 | Z5680 | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. | Putative enzyme; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.525 |
arnC | arnA | Z3512 | Z3513 | Putative sugar transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. | 0.998 |
arnC | yceE | Z3512 | Z1688 | Putative sugar transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.529 |
arnC | yjcP | Z3512 | Z5680 | Putative sugar transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Putative enzyme; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.461 |
emrD | yceE | Z5168 | Z1688 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.713 |
emrD | yceL | Z5168 | Z1702 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Orf, hypothetical protein; Confers resistance to norfloxacin and enoxacin. Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily. | 0.580 |
emrD | ydhE | Z5168 | Z2690 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Putative transport protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.591 |
emrD | yidY | Z5168 | Z5205 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Putative transport protein; Confers resistance to chloramphenicol; Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily. | 0.494 |
emrD | yjcP | Z5168 | Z5680 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Putative enzyme; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.465 |
emrD | yjiO | Z5168 | Z5939 | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | Putative transport protein; Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP; Belongs to the major facilitator superfamily. | 0.433 |
mdtA | yceE | Z3243 | Z1688 | Putative membrane protein; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.516 |
mdtA | yceL | Z3243 | Z1702 | Putative membrane protein; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Orf, hypothetical protein; Confers resistance to norfloxacin and enoxacin. Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily. | 0.632 |
mdtA | ydhE | Z3243 | Z2690 | Putative membrane protein; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative transport protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. | 0.493 |
mdtA | yjcP | Z3243 | Z5680 | Putative membrane protein; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative enzyme; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.706 |
msyB | yceE | Z1686 | Z1688 | Acidic protein suppresses mutants lacking function of protein export; Residues 1 to 125 of 125 are 100.00 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1051. | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.558 |
yceE | arnA | Z1688 | Z3513 | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. | 0.532 |
yceE | arnC | Z1688 | Z3512 | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | Putative sugar transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.529 |
yceE | emrD | Z1688 | Z5168 | Hypothetical protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 2-module integral membrane pump; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B3673. | 0.713 |