STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dadXAlanine racemase 2, catabolic; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. (356 aa)    
Predicted Functional Partners:
dadA
D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.
  
 
 0.999
ddlA
Hypothetical protein; Cell wall formation.
 
 
 0.956
ddlB
D-alanine-D-alanine ligase B, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.944
murF
D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.931
alr
Alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis (By similarity).
  
  
0.916
alaA
Putative aminotransferase; Residues 1 to 405 of 405 are 99.75 pct identical to residues 1 to 405 of 405 from Escherichia coli K-12 Strain MG1655: B2290.
    
 0.817
rhsC
rhsC protein in rhs element, interrupted; Residues 1 to 1397 of 1397 are 97.78 pct identical to residues 1 to 1397 of 1397 from Escherichia coli K-12 Strain MG1655: B0700.
   
  
 0.725
ybeN
Orf, hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.601
lgt
Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
    0.540
putA
Proline dehydrogenase, P5C dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
  
 0.526
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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