STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxaBAltronate oxidoreductase; Residues 1 to 483 of 483 are 99.58 pct identical to residues 1 to 483 of 483 from Escherichia coli K-12 Strain MG1655: B1521; Belongs to the mannitol dehydrogenase family. UxaB subfamily. (483 aa)    
Predicted Functional Partners:
uxaA
Altronate hydrolase; Residues 1 to 495 of 495 are 99.39 pct identical to residues 1 to 495 of 495 from Escherichia coli K-12 Strain MG1655: B3091.
 
 0.996
uxaC
Uronate isomerase; Residues 1 to 470 of 470 are 99.78 pct identical to residues 1 to 470 of 470 from Escherichia coli K-12 Strain MG1655: B3092.
 
 
 0.995
uxuA
Mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.953
kduI
Homolog of pectin degrading enzyme 5-keto 4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
 
   
 0.919
mtlA
PTS system, mannitol-specific enzyme IIABC components; Residues 1 to 637 of 637 are 99.37 pct identical to residues 1 to 637 of 637 from Escherichia coli K-12 Strain MG1655: B3599.
  
  
 0.909
exuT
Transport of hexuronates; Aldohexuronate transport system; Belongs to the major facilitator superfamily. Phthalate permease family.
  
   
 0.835
kduD
2-deoxy-D-gluconate 3-dehydrogenase; Residues 1 to 253 of 253 are 98.81 pct identical to residues 1 to 253 of 253 from Escherichia coli K-12 Strain MG1655: B2842.
  
   
 0.806
yhaG
Putative hydrolase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.
  
 0.722
kdgK
Ketodeoxygluconokinase; Residues 1 to 382 of 382 are 99.21 pct identical to residues 1 to 382 of 382 from Escherichia coli K-12 Strain MG1655: B3526.
 
   
 0.719
ygjR
Orf, hypothetical protein; Residues 1 to 334 of 334 are 98.20 pct identical to residues 1 to 334 of 334 from Escherichia coli K-12 Strain MG1655: B3087.
     
 0.704
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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