node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fumA | fumA-2 | Z2615 | Z0887 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.939 |
fumA | fumB | Z2615 | Z5724 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Fumarase B= fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.938 |
fumA | fumC | Z2615 | Z2614 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Fumarase C= fumarate hydratase Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.993 |
fumA | gltA | Z2615 | Z0873 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Citrate synthase; Residues 1 to 426 of 427 are 99.76 pct identical to residues 1 to 426 of 427 from Escherichia coli K-12 Strain MG1655: B0720; Belongs to the citrate synthase family. | 0.953 |
fumA | maeB | Z2615 | Z3719 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Putative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463. | 0.977 |
fumA | mdh | Z2615 | Z4595 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.988 |
fumA | sdhA | Z2615 | Z0877 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Succinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.967 |
fumA | sdhB | Z2615 | Z0878 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Succinate dehydrogenase, iron sulfur protein; Residues 1 to 238 of 238 are 99.57 pct identical to residues 1 to 238 of 238 from Escherichia coli K-12 Strain MG1655: B0724; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.970 |
fumA | sfcA | Z2615 | Z2231 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | NAD-linked malate dehydrogenase (malic enzyme); Residues 1 to 574 of 574 are 99.47 pct identical to residues 1 to 574 of 574 from Escherichia coli K-12 Strain MG1655: B1479; Belongs to the malic enzymes family. | 0.953 |
fumA | ydbK | Z2615 | Z2332 | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378. | 0.958 |
fumA-2 | fumA | Z0887 | Z2615 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate. | 0.939 |
fumA-2 | fumB | Z0887 | Z5724 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase B= fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.939 |
fumA-2 | fumC | Z0887 | Z2614 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase C= fumarate hydratase Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.956 |
fumA-2 | gltA | Z0887 | Z0873 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase; Residues 1 to 426 of 427 are 99.76 pct identical to residues 1 to 426 of 427 from Escherichia coli K-12 Strain MG1655: B0720; Belongs to the citrate synthase family. | 0.930 |
fumA-2 | maeB | Z0887 | Z3719 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463. | 0.977 |
fumA-2 | mdh | Z0887 | Z4595 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.985 |
fumA-2 | sdhA | Z0887 | Z0877 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.962 |
fumA-2 | sdhB | Z0887 | Z0878 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, iron sulfur protein; Residues 1 to 238 of 238 are 99.57 pct identical to residues 1 to 238 of 238 from Escherichia coli K-12 Strain MG1655: B0724; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.960 |
fumA-2 | sfcA | Z0887 | Z2231 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NAD-linked malate dehydrogenase (malic enzyme); Residues 1 to 574 of 574 are 99.47 pct identical to residues 1 to 574 of 574 from Escherichia coli K-12 Strain MG1655: B1479; Belongs to the malic enzymes family. | 0.961 |
fumA-2 | ydbK | Z0887 | Z2332 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378. | 0.958 |