STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykFPyruvate kinase I (formerly F), fructose stimulated; Residues 1 to 470 of 470 are 100.00 pct identical to residues 1 to 470 of 470 from Escherichia coli K-12 Strain MG1655: B1676. (470 aa)    
Predicted Functional Partners:
ydbK
Putative oxidoreductase, Fe-S subunit; Residues 1 to 1174 of 1174 are 99.57 pct identical to residues 1 to 1174 of 1174 from Escherichia coli K-12 Strain MG1655: B1378.
  
 0.988
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.986
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.975
pgi
Glucosephosphate isomerase; Residues 1 to 549 of 549 are 100.00 pct identical to residues 1 to 549 of 549 from Escherichia coli K-12 Strain MG1655: B4025; Belongs to the GPI family.
  
 
 0.965
ldhA
Fermentative D-lactate dehydrogenase, NAD-dependent; Residues 1 to 329 of 329 are 99.69 pct identical to residues 1 to 329 of 329 from Escherichia coli K-12 Strain MG1655: B1380; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.958
maeB
Putative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463.
  
 0.957
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.956
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.953
sfcA
NAD-linked malate dehydrogenase (malic enzyme); Residues 1 to 574 of 574 are 99.47 pct identical to residues 1 to 574 of 574 from Escherichia coli K-12 Strain MG1655: B1479; Belongs to the malic enzymes family.
  
 0.947
tktA
Transketolase 1 isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.944
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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