STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
otsATrehalose-6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (474 aa)    
Predicted Functional Partners:
otsB
Trehalose-6-phosphate phophatase, biosynthetic; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 
 0.999
treC
Trehalase 6-P hydrolase; Residues 1 to 551 of 551 are 98.72 pct identical to residues 1 to 551 of 551 from Escherichia coli K-12 Strain MG1655: B4239.
  
 
 0.930
galU
Glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
    
 0.914
galF
Homolog of Salmonella UTP--glucose-1-P uridyltransferase, probably a UDP-gal transferase; Residues 1 to 297 of 297 are 100.00 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B2042.
    
 0.914
treB
PTS system enzyme II, trehalose specific; Residues 1 to 473 of 473 are 99.57 pct identical to residues 1 to 473 of 473 from Escherichia coli K-12 Strain MG1655: B4240.
     
 0.909
yhjOP
Putative cellulose synthase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix (By similarity).
  
 
  0.902
crr
PTS system, glucose-specific IIA component; Residues 1 to 169 of 169 are 99.40 pct identical to residues 1 to 169 of 169 from Escherichia coli K-12 Strain MG1655: B2417.
     
  0.900
glvA
Putative 6-phospho-beta-glucosidase; Residues 1 to 440 of 440 are 75.05 pct identical to residues 1 to 441 of 441 from GenPept 118 : gi|2145152|gb|AAB63015.1| (U81185) MalH [Fusobacterium mortiferum].
    
  0.900
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
     
 0.855
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
    0.851
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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