STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliAFlagellar biosynthesis; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa)    
Predicted Functional Partners:
flgM
anti-FliA (anti-sigma) factor; Residues 1 to 97 of 97 are 98.96 pct identical to residues 1 to 97 of 97 from Escherichia coli K-12 Strain MG1655: B1071.
 
 0.999
fliZ
Orf, hypothetical protein; Residues 1 to 195 of 195 are 98.97 pct identical to residues 1 to 195 of 195 from Escherichia coli K-12 Strain MG1655: B1921.
  
  
 0.994
flgB
Flagellar biosynthesis, cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.988
fliC
Flagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.987
flgC
Flagellar biosynthesis, cell-proximal portion of basal-body rod; Residues 1 to 134 of 134 are 100.00 pct identical to residues 1 to 134 of 134 from Escherichia coli K-12 Strain MG1655: B1074; Belongs to the flagella basal body rod proteins family.
 
 
 0.978
fliD
Flagellar biosynthesis; Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
 
  
 0.973
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
 
 0.973
flgD
Flagellar biosynthesis, initiation of hook assembly; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.969
flgE
Flagellar biosynthesis, hook protein; Residues 1 to 401 of 401 are 94.77 pct identical to residues 1 to 402 of 402 from Escherichia coli K-12 Strain MG1655: B1076.
 
  
 0.964
fliI
Flagellum-specific ATP synthase; Residues 40 to 496 of 496 are 100.00 pct identical to residues 1 to 457 of 457 from Escherichia coli K-12 Strain MG1655: B1941.
 
 
 0.960
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.