STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galFHomolog of Salmonella UTP--glucose-1-P uridyltransferase, probably a UDP-gal transferase; Residues 1 to 297 of 297 are 100.00 pct identical to residues 1 to 297 of 297 from Escherichia coli K-12 Strain MG1655: B2042. (297 aa)    
Predicted Functional Partners:
ugd
UDP-glucose 6-dehydrogenase; Residues 1 to 388 of 388 are 99.22 pct identical to residues 1 to 388 of 388 from Escherichia coli K-12 Strain MG1655: B2028; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 0.986
galE
UDP-galactose-4-epimerase; Residues 1 to 338 of 338 are 99.70 pct identical to residues 1 to 338 of 338 from Escherichia coli K-12 Strain MG1655: B0759; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
  
 0.959
galU
Glucose-1-phosphate uridylyltransferase; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
  
 
 
0.923
rffH
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
0.923
pgm
Phosphoglucomutase; Residues 1 to 546 of 546 are 99.63 pct identical to residues 1 to 546 of 546 from Escherichia coli K-12 Strain MG1655: B0688.
    
 0.920
otsA
Trehalose-6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
    
 0.914
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
     
 0.912
yhjOP
Putative cellulose synthase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix (By similarity).
  
 
 0.912
galT
Galactose-1-phosphate uridylyltransferase; Residues 1 to 348 of 348 are 99.42 pct identical to residues 1 to 348 of 348 from Escherichia coli K-12 Strain MG1655: B0758; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
     
 0.910
glgX
Part of glycogen operon, a glycosyl hydrolase, debranching enzyme; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
     
 0.910
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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