STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wzcOrf, hypothetical protein; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg (By similarity); Belongs to the etk/wzc family. (732 aa)    
Predicted Functional Partners:
wza
Putative polysaccharide export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.
 
 
 0.999
wcaJ
Putative colanic acid biosynthsis UDP-glucose lipid carrier transferase; Residues 1 to 464 of 464 are 99.56 pct identical to residues 1 to 464 of 464 from Escherichia coli K-12 Strain MG1655: B2047.
 
  
 0.997
wzb
Probable protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI).
 
 
 0.997
yccZ
Putative function in exopolysaccharide production; May be involved in polysaccharide transport; Belongs to the BexD/CtrA/VexA family.
 
 
 0.982
ymcB
Orf, hypothetical protein; Residues 1 to 248 of 248 are 98.38 pct identical to residues 1 to 248 of 248 from Escherichia coli K-12 Strain MG1655: B0985.
  
 
 0.945
yccC
Orf, hypothetical protein; Residues 1 to 726 of 726 are 99.86 pct identical to residues 1 to 726 of 726 from Escherichia coli K-12 Strain MG1655: B0981.
 
 
0.943
wzxC
Probable export protein; Residues 1 to 492 of 492 are 99.18 pct identical to residues 1 to 492 of 492 from Escherichia coli K-12 Strain MG1655: B2046.
 
  
 0.928
wcaA
Putative regulator; Residues 1 to 279 of 279 are 99.64 pct identical to residues 1 to 279 of 279 from Escherichia coli K-12 Strain MG1655: B2059.
 
  
 0.928
yccY
Putative phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
 
 0.901
wcaF
Putative transferase; Residues 1 to 182 of 182 are 98.90 pct identical to residues 1 to 182 of 182 from Escherichia coli K-12 Strain MG1655: B2054.
 
  
 0.891
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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