STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
napAProbable nitrate reductase 3; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)    
Predicted Functional Partners:
napB
Cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
 
 0.999
napD
Orf, hypothetical protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
 
 
 0.999
napF
Ferredoxin-type protein: electron transfer; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
 
  
 0.996
napC
Cytochrome c-type protein; Mediates electron flow from quinones to the NapAB complex.
 
 
 0.995
napH
Ferredoxin-type protein: electron transfer; Residues 1 to 287 of 287 are 99.65 pct identical to residues 1 to 287 of 287 from Escherichia coli K-12 Strain MG1655: B2204.
 
  
 0.991
napG
Ferredoxin-type protein: electron transfer; Residues 1 to 231 of 231 are 99.56 pct identical to residues 1 to 231 of 231 from Escherichia coli K-12 Strain MG1655: B2205.
 
 
 0.989
narG
Nitrate reductase 1, alpha subunit; Residues 1 to 1247 of 1247 are 99.91 pct identical to residues 1 to 1247 of 1247 from Escherichia coli K-12 Strain MG1655: B1224; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.974
narZ
Cryptic nitrate reductase 2, alpha subunit; Residues 1 to 1246 of 1246 are 99.19 pct identical to residues 1 to 1246 of 1246 from Escherichia coli K-12 Strain MG1655: B1468; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.974
nrfA
Periplasmic cytochrome c(552): plays a role in nitrite reduction; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
  
 
 0.966
nirB
Nitrite reductase (NAD(P)H) subunit; Residues 1 to 847 of 847 are 99.76 pct identical to residues 1 to 847 of 847 from Escherichia coli K-12 Strain MG1655: B3365; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 0.946
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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