STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsdAD-serine dehydratase (deaminase); Residues 1 to 442 of 442 are 99.09 pct identical to residues 1 to 442 of 442 from Escherichia coli K-12 Strain MG1655: B2366. (442 aa)    
Predicted Functional Partners:
dsdX
D-serine permease; Residues 1 to 72 of 72 are 100.00 pct identical to residues 374 to 445 of 445 from GenPept 118 : gi|1788707|gb|AAC75424.1| (AE000324) transport system permease (serine?) [Escherichia coli].
 
  
 0.979
sdaA
L-serine deaminase; Residues 1 to 454 of 454 are 99.77 pct identical to residues 1 to 454 of 454 from Escherichia coli K-12 Strain MG1655: B1814; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.927
sdaB
L-serine dehydratase (deaminase), L-SD2; Residues 1 to 455 of 455 are 99.56 pct identical to residues 1 to 455 of 455 from Escherichia coli K-12 Strain MG1655: B2797; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.927
tdcG_3
Putative L-serine deaminase; Residues 3 to 455 of 456 are 73.28 pct identical to residues 1 to 453 of 454 from Escherichia coli K-12 Strain MG1655: B1814; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.914
tdcB
Threonine dehydratase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to [...]
     
 0.906
ilvA
Threonine deaminase (dehydratase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.906
Z3626
Sucrose specific transcriptional regulator; Residues 1 to 331 of 331 are 99.39 pct identical to residues 1 to 331 of 331 from GenPept 118 : gi|608709|emb|CAA57220.1| (X81461) sucrose specific repressor [Escherichia coli].
     
 0.824
ycdW
Putative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
     
  0.800
aldA
Aldehyde dehydrogenase, NAD-linked; Residues 1 to 479 of 479 are 99.79 pct identical to residues 1 to 479 of 479 from Escherichia coli K-12 Strain MG1655: B1415; Belongs to the aldehyde dehydrogenase family.
     
  0.800
gloA
Hypothetical protein; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
  0.800
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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