node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
relA | rplS | Z4099 | Z3900 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.999 |
relA | rplT | Z4099 | Z2745 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 50S ribosomal subunit protein L20, and regulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.999 |
relA | rplY | Z4099 | Z3444 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. | 0.999 |
relA | rpmF | Z4099 | Z1728 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 50S ribosomal subunit protein L32; Residues 1 to 57 of 57 are 100.00 pct identical to residues 1 to 57 of 57 from Escherichia coli K-12 Strain MG1655: B1089; Belongs to the bacterial ribosomal protein bL32 family. | 0.999 |
relA | rpmI | Z4099 | Z2746 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 50S ribosomal subunit protein A; Residues 1 to 65 of 65 are 100.00 pct identical to residues 1 to 65 of 65 from Escherichia coli K-12 Strain MG1655: B1717; Belongs to the bacterial ribosomal protein bL35 family. | 0.999 |
relA | rpsB | Z4099 | Z0180 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 30S ribosomal subunit protein S2; Residues 1 to 241 of 241 are 100.00 pct identical to residues 1 to 241 of 241 from Escherichia coli K-12 Strain MG1655: B0169. | 0.999 |
relA | rpsO | Z4099 | Z4526 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.999 |
relA | rpsP | Z4099 | Z3903 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 30S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. | 0.999 |
relA | rpsT | Z4099 | Z0027 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | 0.999 |
relA | rpsU | Z4099 | Z4418 | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 30S ribosomal subunit protein S21; Residues 1 to 71 of 71 are 100.00 pct identical to residues 1 to 71 of 71 from Escherichia coli K-12 Strain MG1655: B3065; Belongs to the bacterial ribosomal protein bS21 family. | 0.999 |
rplS | relA | Z3900 | Z4099 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | (p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity). | 0.999 |
rplS | rplT | Z3900 | Z2745 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 50S ribosomal subunit protein L20, and regulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity). | 0.994 |
rplS | rplY | Z3900 | Z3444 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. | 0.971 |
rplS | rpmF | Z3900 | Z1728 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 50S ribosomal subunit protein L32; Residues 1 to 57 of 57 are 100.00 pct identical to residues 1 to 57 of 57 from Escherichia coli K-12 Strain MG1655: B1089; Belongs to the bacterial ribosomal protein bL32 family. | 0.974 |
rplS | rpmI | Z3900 | Z2746 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 50S ribosomal subunit protein A; Residues 1 to 65 of 65 are 100.00 pct identical to residues 1 to 65 of 65 from Escherichia coli K-12 Strain MG1655: B1717; Belongs to the bacterial ribosomal protein bL35 family. | 0.972 |
rplS | rpsB | Z3900 | Z0180 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal subunit protein S2; Residues 1 to 241 of 241 are 100.00 pct identical to residues 1 to 241 of 241 from Escherichia coli K-12 Strain MG1655: B0169. | 0.991 |
rplS | rpsO | Z3900 | Z4526 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.986 |
rplS | rpsP | Z3900 | Z3903 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal subunit protein S16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity. | 0.996 |
rplS | rpsT | Z3900 | Z0027 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | 0.949 |
rplS | rpsU | Z3900 | Z4418 | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 30S ribosomal subunit protein S21; Residues 1 to 71 of 71 are 100.00 pct identical to residues 1 to 71 of 71 from Escherichia coli K-12 Strain MG1655: B3065; Belongs to the bacterial ribosomal protein bS21 family. | 0.955 |