STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthetase; Residues 1 to 315 of 315 are 100.00 pct identical to residues 1 to 315 of 316 from Escherichia coli K-12 Strain MG1655: B2947. (315 aa)    
Predicted Functional Partners:
gshA
Gamma-glutamate-cysteine ligase; Residues 1 to 518 of 518 are 99.80 pct identical to residues 1 to 518 of 518 from Escherichia coli K-12 Strain MG1655: B2688; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
 
 
 0.985
ggt
Gamma-glutamyltranspeptidase; Residues 1 to 581 of 581 are 98.27 pct identical to residues 1 to 580 of 580 from Escherichia coli K-12 Strain MG1655: B3447.
    
 0.954
gor
Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500.
     
 0.951
pepD
Aminoacyl-histidine dipeptidase (peptidase D); Residues 1 to 485 of 485 are 99.58 pct identical to residues 1 to 485 of 485 from Escherichia coli K-12 Strain MG1655: B0237.
     
 0.948
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Required for plasmid ColE1 site-specific recombination but not in its aminopeptidase activity. Could act as a structural component of the putative nucleoprotein complex in which the Xer recombination reaction takes place (By similarity); Belongs to the peptidase M17 family.
   
 
 0.948
gst
Glutathionine S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Beta family.
  
  
 0.923
btuE
Vitamin B12 transport; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
    
 0.920
pepB
Putative peptidase; Probably plays an important role in intracellular peptide degradation.
   
 
 0.920
ybdK
Orf, hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
    
 0.914
pepN
Aminopeptidase N; Residues 1 to 870 of 870 are 99.19 pct identical to residues 1 to 870 of 870 from Escherichia coli K-12 Strain MG1655: B0932.
    
 0.910
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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