STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttdBL-tartrate dehydratase, subunit B; Residues 1 to 201 of 201 are 99.00 pct identical to residues 1 to 201 of 201 from Escherichia coli K-12 Strain MG1655: B3062. (201 aa)    
Predicted Functional Partners:
ttdA
L-tartrate dehydratase, subunit A; Residues 1 to 303 of 303 are 99.00 pct identical to residues 1 to 303 of 303 from Escherichia coli K-12 Strain MG1655: B3061; Belongs to the class-I fumarase family.
 
 0.999
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.937
maeB
Putative multimodular enzyme; Residues 1 to 759 of 759 are 99.86 pct identical to residues 1 to 759 of 759 from Escherichia coli K-12 Strain MG1655: B2463.
 
 
 0.928
gltA
Citrate synthase; Residues 1 to 426 of 427 are 99.76 pct identical to residues 1 to 426 of 427 from Escherichia coli K-12 Strain MG1655: B0720; Belongs to the citrate synthase family.
  
 
 0.923
yeaU
Putative tartrate dehydrogenase; Residues 1 to 361 of 361 are 99.72 pct identical to residues 1 to 361 of 361 from Escherichia coli K-12 Strain MG1655: B1800.
 
 
 0.919
ygjE
Orf, hypothetical protein; Catalyzes the uptake of tartrate in exchange for intracellular succinate. Essential for anaerobic L-tartrate fermentation (By similarity).
 
   
 0.879
fumA-2
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
0.859
fumA
Fumarase A = fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80% of the fumarase activity when the bacteria grow aerobically. To a lesser extent, also displays D-tartrate dehydratase activity in vitro, but is not able to convert (R)-malate, L-tartrate or meso-tartrate. Can also catalyze the isomerization of enol- to keto-oxaloacetate.
 
 
0.858
fumB
Fumarase B= fumarate hydratase Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
0.857
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.842
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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