STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxaCUronate isomerase; Residues 1 to 470 of 470 are 99.78 pct identical to residues 1 to 470 of 470 from Escherichia coli K-12 Strain MG1655: B3092. (470 aa)    
Predicted Functional Partners:
uxaB
Altronate oxidoreductase; Residues 1 to 483 of 483 are 99.58 pct identical to residues 1 to 483 of 483 from Escherichia coli K-12 Strain MG1655: B1521; Belongs to the mannitol dehydrogenase family. UxaB subfamily.
 
 
 0.995
uxuB
Mannonate oxidoreductase; Residues 1 to 486 of 486 are 99.58 pct identical to residues 1 to 486 of 486 from Escherichia coli K-12 Strain MG1655: B4323; Belongs to the mannitol dehydrogenase family.
 
 
 0.994
uxuA
Mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.993
uxaA
Altronate hydrolase; Residues 1 to 495 of 495 are 99.39 pct identical to residues 1 to 495 of 495 from Escherichia coli K-12 Strain MG1655: B3091.
 
  
 0.989
uidA_1
Partial beta-D-glucuronidase; Residues 1 to 368 of 368 are 99.18 pct identical to residues 236 to 603 of 603 from Escherichia coli K-12 Strain MG1655: B1617.
 
 
 0.960
kduI
Homolog of pectin degrading enzyme 5-keto 4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
 
  
 0.939
exuT
Transport of hexuronates; Aldohexuronate transport system; Belongs to the major facilitator superfamily. Phthalate permease family.
 
   
 0.897
kdgK
Ketodeoxygluconokinase; Residues 1 to 382 of 382 are 99.21 pct identical to residues 1 to 382 of 382 from Escherichia coli K-12 Strain MG1655: B3526.
 
   
 0.832
kduD
2-deoxy-D-gluconate 3-dehydrogenase; Residues 1 to 253 of 253 are 98.81 pct identical to residues 1 to 253 of 253 from Escherichia coli K-12 Strain MG1655: B2842.
 
   
 0.818
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
     
 0.813
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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