STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (477 aa)    
Predicted Functional Partners:
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
 
 
 0.999
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.999
glgX
Part of glycogen operon, a glycosyl hydrolase, debranching enzyme; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
  
 0.997
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.995
malQ
4-alpha-glucanotransferase (amylomaltase); Residues 1 to 694 of 694 are 98.84 pct identical to residues 1 to 694 of 694 from Escherichia coli K-12 Strain MG1655: B3416.
 
 
 0.979
malP
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.965
adhE
CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction (By similarity); In the N-terminal section; belongs to the aldehyde dehydrogenase family.
  
  
 0.747
ycjM
Putative polysaccharide hydrolase; Residues 1 to 434 of 434 are 95.39 pct identical to residues 135 to 568 of 568 from Escherichia coli K-12 Strain MG1655: B1309.
  
  
 0.636
yeaG
Hypothetical protein; Residues 1 to 644 of 644 are 100.00 pct identical to residues 1 to 644 of 644 from Escherichia coli K-12 Strain MG1655: B1783; Belongs to the PrkA family.
   
    0.593
malZ
Maltodextrin glucosidase; Residues 1 to 605 of 605 are 98.67 pct identical to residues 1 to 605 of 605 from Escherichia coli K-12 Strain MG1655: B0403; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.573
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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