STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmG50S ribosomal subunit protein L33; Residues 1 to 55 of 55 are 100.00 pct identical to residues 1 to 55 of 55 from Escherichia coli K-12 Strain MG1655: B3636; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)    
Predicted Functional Partners:
relA
(p)ppGpp synthetase I (GTP pyrophosphokinase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity).
    
   0.999
rplM
50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.999
tufA
Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 0.999
rpmB
50S ribosomal subunit protein L28; Residues 1 to 78 of 78 are 100.00 pct identical to residues 1 to 78 of 78 from Escherichia coli K-12 Strain MG1655: B3637; Belongs to the bacterial ribosomal protein bL28 family.
 
 
 0.999
rplK
50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.999
rplJ
50S ribosomal subunit protein L10; Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity); Belongs to the universal ribosomal protein uL10 family.
  
 
 0.999
rpsR
30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
 
 0.979
rpsJ
30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.978
rplL
50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.974
rpmA
50S ribosomal subunit protein L27; Residues 1 to 85 of 85 are 100.00 pct identical to residues 1 to 85 of 85 from Escherichia coli K-12 Strain MG1655: B3185; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.973
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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