STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pstBATP-binding component of high-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)    
Predicted Functional Partners:
phoU
Negative regulator for pho regulon and putative enzyme in phosphate metabolism; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
 
  
 0.999
pstA
High-affinity phosphate-specific transport system; Residues 1 to 296 of 296 are 99.66 pct identical to residues 1 to 296 of 296 from Escherichia coli K-12 Strain MG1655: B3726.
 
 
 0.999
pstC
High-affinity phosphate-specific transport system, cytoplasmic membrane component; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.999
pstS
High-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
 0.999
Orf-15
Orf; Residues 1 to 74 of 502 are 83.78 pct identical to residues 4 to 77 of 97 from Escherichia coli K-12 Strain MG1655: B3427.
 
 
 0.951
Orf-14
Orf; Residues 133 to 319 of 330 are 32.08 pct identical to residues 98 to 269 of 278 from GenPept 118 : gi|2622859|gb|AAB86198.1| (AE000929) phosphate-binding protein PstS homolog [Methanobacterium thermoautotrophicum].
 
 
 0.942
cydD
ATP-binding component of cytochrome-related transport, Zn sensitive; Residues 1 to 588 of 588 are 99.31 pct identical to residues 1 to 588 of 588 from Escherichia coli K-12 Strain MG1655: B0887.
 
     
0.894
phoR
Positive and negative sensor protein for pho regulon; Residues 1 to 431 of 431 are 99.07 pct identical to residues 1 to 431 of 431 from Escherichia coli K-12 Strain MG1655: B0400.
 
   
 0.888
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
   
 0.767
gltB
Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212.
     
 0.705
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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