node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ahpC | ahpF | Z0749 | Z0750 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | 0.997 |
ahpC | gor | Z0749 | Z4900 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | 0.654 |
ahpC | grxA | Z0749 | Z1076 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Glutaredoxin1 redox coenzyme for glutathione-dependent ribonucleotide reductase; Residues 1 to 85 of 85 are 98.82 pct identical to residues 1 to 85 of 85 from Escherichia coli K-12 Strain MG1655: B0849. | 0.432 |
ahpC | katE | Z0749 | Z2761 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.877 |
ahpC | katG | Z0749 | Z5497 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.830 |
ahpC | oxyR | Z0749 | Z5519 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | 0.799 |
ahpC | rpoS | Z0749 | Z4049 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | RNA polymerase, sigma S (sigma38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.427 |
ahpC | sodA | Z0749 | Z5453 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Superoxide dismutase, manganese; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.856 |
ahpF | ahpC | Z0750 | Z0749 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.997 |
ahpF | grxA | Z0750 | Z1076 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Glutaredoxin1 redox coenzyme for glutathione-dependent ribonucleotide reductase; Residues 1 to 85 of 85 are 98.82 pct identical to residues 1 to 85 of 85 from Escherichia coli K-12 Strain MG1655: B0849. | 0.666 |
ahpF | katE | Z0750 | Z2761 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.719 |
ahpF | katG | Z0750 | Z5497 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.750 |
ahpF | oxyR | Z0750 | Z5519 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | 0.784 |
ahpF | sodA | Z0750 | Z5453 | Alkyl hydroperoxide reductase, F52a subunit; Residues 1 to 531 of 531 are 100.00 pct identical to residues 1 to 531 of 531 from Escherichia coli K-12 Strain MG1655: B0606. | Superoxide dismutase, manganese; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.682 |
gor | ahpC | Z4900 | Z0749 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.654 |
gor | grxA | Z4900 | Z1076 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Glutaredoxin1 redox coenzyme for glutathione-dependent ribonucleotide reductase; Residues 1 to 85 of 85 are 98.82 pct identical to residues 1 to 85 of 85 from Escherichia coli K-12 Strain MG1655: B0849. | 0.822 |
gor | katE | Z4900 | Z2761 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.529 |
gor | katG | Z4900 | Z5497 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.591 |
gor | oxyR | Z4900 | Z5519 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | 0.755 |
gor | sodA | Z4900 | Z5453 | Glutathione oxidoreductase; Residues 1 to 450 of 450 are 99.33 pct identical to residues 1 to 450 of 450 from Escherichia coli K-12 Strain MG1655: B3500. | Superoxide dismutase, manganese; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.703 |