Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acrR | marR | Z0579 | Z2171 | acrAB operon repressor; Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B0464. | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | 0.817 |
| acrR | soxR | Z0579 | Z5662 | acrAB operon repressor; Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B0464. | Redox-sensing activator of soxS; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress. Upon reduction of 2Fe-2S cluster, SoxR reversibly loses its transcriptional activity, but retains its DNA binding affinity (By similarity). | 0.844 |
| acrR | soxS | Z0579 | Z5661 | acrAB operon repressor; Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B0464. | Regulation of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity). | 0.814 |
| acrR | tolC | Z0579 | Z4392 | acrAB operon repressor; Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B0464. | Outer membrane channel; Residues 1 to 495 of 495 are 99.79 pct identical to residues 1 to 495 of 495 from Escherichia coli K-12 Strain MG1655: B3035. | 0.800 |
| araC | marR | Z0073 | Z2171 | Transcriptional regulator for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | 0.706 |
| araC | rpoD | Z0073 | Z4420 | Transcriptional regulator for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | RNA polymerase, sigma(70) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.579 |
| araC | soxS | Z0073 | Z5661 | Transcriptional regulator for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | Regulation of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity). | 0.876 |
| marR | acrR | Z2171 | Z0579 | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | acrAB operon repressor; Residues 1 to 215 of 215 are 99.53 pct identical to residues 1 to 215 of 215 from Escherichia coli K-12 Strain MG1655: B0464. | 0.817 |
| marR | araC | Z2171 | Z0073 | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | Transcriptional regulator for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose. | 0.706 |
| marR | soxR | Z2171 | Z5662 | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | Redox-sensing activator of soxS; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress. Upon reduction of 2Fe-2S cluster, SoxR reversibly loses its transcriptional activity, but retains its DNA binding affinity (By similarity). | 0.788 |
| marR | soxS | Z2171 | Z5661 | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | Regulation of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity). | 0.794 |
| marR | tolC | Z2171 | Z4392 | Multiple antibiotic resistance protein; Residues 1 to 125 of 125 are 98.40 pct identical to residues 1 to 125 of 125 from Escherichia coli K-12 Strain MG1655: B1530. | Outer membrane channel; Residues 1 to 495 of 495 are 99.79 pct identical to residues 1 to 495 of 495 from Escherichia coli K-12 Strain MG1655: B3035. | 0.613 |
| oxyR | sodA | Z5519 | Z5453 | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | Superoxide dismutase, manganese; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.769 |
| oxyR | soxR | Z5519 | Z5662 | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | Redox-sensing activator of soxS; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress. Upon reduction of 2Fe-2S cluster, SoxR reversibly loses its transcriptional activity, but retains its DNA binding affinity (By similarity). | 0.810 |
| oxyR | soxS | Z5519 | Z5661 | Activator, hydrogen peroxide-inducible genes; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation a [...] | Regulation of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity). | 0.777 |
| rpoA | rpoC | Z4665 | Z5561 | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoD | Z4665 | Z4420 | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, sigma(70) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
| rpoA | soxS | Z4665 | Z5661 | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Regulation of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity). | 0.814 |
| rpoC | rpoA | Z5561 | Z4665 | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoC | rpoD | Z5561 | Z4420 | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, sigma(70) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
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