node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
add | apt | Z2628 | Z0586 | Adenosine deaminase; Residues 1 to 333 of 333 are 99.39 pct identical to residues 1 to 333 of 333 from Escherichia coli K-12 Strain MG1655: B1623; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.705 |
add | deoD | Z2628 | Z5986 | Adenosine deaminase; Residues 1 to 333 of 333 are 99.39 pct identical to residues 1 to 333 of 333 from Escherichia coli K-12 Strain MG1655: B1623; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | 0.961 |
apt | add | Z0586 | Z2628 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenosine deaminase; Residues 1 to 333 of 333 are 99.39 pct identical to residues 1 to 333 of 333 from Escherichia coli K-12 Strain MG1655: B1623; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.705 |
apt | cdd | Z0586 | Z3398 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.413 |
apt | deoA | Z0586 | Z5984 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.636 |
apt | deoD | Z0586 | Z5986 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | 0.952 |
apt | tdk | Z0586 | Z2015 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Thymidine kinase; Phosphorylates both thymidine and deoxyuridine. | 0.735 |
cdd | apt | Z3398 | Z0586 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.413 |
cdd | deoA | Z3398 | Z5984 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.969 |
cdd | deoC | Z3398 | Z5983 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 0.472 |
cdd | deoD | Z3398 | Z5986 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | 0.925 |
cdd | tdk | Z3398 | Z2015 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine kinase; Phosphorylates both thymidine and deoxyuridine. | 0.955 |
cdd | udp | Z3398 | Z5353 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.989 |
cobB | deoD | Z1761 | Z5986 | Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | 0.920 |
deoA | apt | Z5984 | Z0586 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.636 |
deoA | cdd | Z5984 | Z3398 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.969 |
deoA | deoB | Z5984 | Z5985 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.997 |
deoA | deoC | Z5984 | Z5983 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 0.991 |
deoA | deoD | Z5984 | Z5986 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Purine-nucleoside phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules; Belongs to the PNP/UDP phosphorylase family. | 0.993 |
deoA | preT | Z5984 | Z3401 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity). | 0.911 |