STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAS19697.1Heat shock protein Hsp40. (151 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK (Heat shock protein HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.972
EAS19834.1
Chaperone/heat shock protein, htpG; Molecular chaperone. Has ATPase activity.
  
 0.943
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
  
 
 0.831
EAS19663.1
Peptidyl-prolyl cis-trans isomerase (PPIase).
   
 0.818
EAS19943.1
Peptidyl-prolyl cis-trans isomerase (Ppi).
   
 0.818
EAS19698.1
Short chain dehydrogenase.
 
 
   0.801
rplQ
50S ribosomal protein L17 (rplQ).
  
   0.800
EAS19705.1
ATP-dependent RNA helicase.
  
 
   0.791
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.789
rplM
RplM, large ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.788
Your Current Organism:
Flavobacteria bacterium BBFL7
NCBI taxonomy Id: 156586
Other names: F. bacterium BBFL7, marine CFB-group bacterium BBFL7, marine bacterium BBFL7
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