node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmc1_0026 | Mmc1_0027 | Mmc1_0026 | Mmc1_0027 | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.951 |
Mmc1_0026 | Mmc1_0706 | Mmc1_0026 | Mmc1_0706 | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin). | 0.547 |
Mmc1_0026 | hemC | Mmc1_0026 | Mmc1_0737 | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.477 |
Mmc1_0026 | hemE | Mmc1_0026 | Mmc1_0025 | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.990 |
Mmc1_0026 | hemH | Mmc1_0026 | Mmc1_1701 | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.442 |
Mmc1_0027 | Mmc1_0026 | Mmc1_0027 | Mmc1_0026 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.951 |
Mmc1_0027 | Mmc1_3144 | Mmc1_0027 | Mmc1_3144 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gvi:glr4358 5-aminolevulinate dehydratase; Belongs to the ALAD family. | 0.510 |
Mmc1_0027 | hemC | Mmc1_0027 | Mmc1_0737 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.562 |
Mmc1_0027 | hemE | Mmc1_0027 | Mmc1_0025 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.998 |
Mmc1_0027 | hemH | Mmc1_0027 | Mmc1_1701 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.988 |
Mmc1_0027 | hemL | Mmc1_0027 | Mmc1_0093 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: psp:PSPPH_4384 glutamate-1-semialdehyde-2,1-aminomutase. | 0.436 |
Mmc1_0706 | Mmc1_0026 | Mmc1_0706 | Mmc1_0026 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin). | KEGG: tcx:Tcr_0501 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.547 |
Mmc1_0706 | Mmc1_2225 | Mmc1_0706 | Mmc1_2225 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin). | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ret:RHE_CH02484 uroporphyrin-III C-methyltransferase protein; Belongs to the precorrin methyltransferase family. | 0.456 |
Mmc1_0706 | hemE | Mmc1_0706 | Mmc1_0025 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.621 |
Mmc1_0706 | nifH | Mmc1_0706 | Mmc1_1202 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin). | Mo-nitrogenase iron protein subunit NifH; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. | 0.646 |
Mmc1_0736 | Mmc1_2225 | Mmc1_0736 | Mmc1_2225 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ret:RHE_CH02484 uroporphyrin-III C-methyltransferase protein; Belongs to the precorrin methyltransferase family. | 0.995 |
Mmc1_0736 | Mmc1_3144 | Mmc1_0736 | Mmc1_3144 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gvi:glr4358 5-aminolevulinate dehydratase; Belongs to the ALAD family. | 0.929 |
Mmc1_0736 | hemC | Mmc1_0736 | Mmc1_0737 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
Mmc1_0736 | hemE | Mmc1_0736 | Mmc1_0025 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.935 |
Mmc1_0736 | hemH | Mmc1_0736 | Mmc1_1701 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.407 |