node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmc1_0264 | purC | Mmc1_0264 | Mmc1_0497 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | KEGG: mag:amb1539 phosphoribosylaminoimidazolesuccinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.849 |
Mmc1_0264 | purD | Mmc1_0264 | Mmc1_3465 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | KEGG: pca:Pcar_2231 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.570 |
Mmc1_0264 | purE | Mmc1_0264 | Mmc1_3464 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.826 |
Mmc1_0264 | purF | Mmc1_0264 | Mmc1_0265 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.937 |
Mmc1_0264 | purH | Mmc1_0264 | Mmc1_3468 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase; KEGG: gsu:GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.566 |
Mmc1_0264 | purL | Mmc1_0264 | Mmc1_0498 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.995 |
Mmc1_0264 | purM | Mmc1_0264 | Mmc1_2316 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: reu:Reut_A2773 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.838 |
Mmc1_0264 | purN | Mmc1_0264 | Mmc1_2317 | PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.590 |
Mmc1_1065 | glyA | Mmc1_1065 | Mmc1_0169 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.879 |
Mmc1_1065 | purC | Mmc1_1065 | Mmc1_0497 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mag:amb1539 phosphoribosylaminoimidazolesuccinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.997 |
Mmc1_1065 | purD | Mmc1_1065 | Mmc1_3465 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: pca:Pcar_2231 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.961 |
Mmc1_1065 | purE | Mmc1_1065 | Mmc1_3464 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.955 |
Mmc1_1065 | purF | Mmc1_1065 | Mmc1_0265 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.969 |
Mmc1_1065 | purH | Mmc1_1065 | Mmc1_3468 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase; KEGG: gsu:GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.995 |
Mmc1_1065 | purL | Mmc1_1065 | Mmc1_0498 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
Mmc1_1065 | purM | Mmc1_1065 | Mmc1_2316 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: reu:Reut_A2773 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.905 |
Mmc1_1065 | purN | Mmc1_1065 | Mmc1_2317 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.915 |
glyA | Mmc1_1065 | Mmc1_0169 | Mmc1_1065 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: vpa:VP1128 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.879 |
glyA | purC | Mmc1_0169 | Mmc1_0497 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: mag:amb1539 phosphoribosylaminoimidazolesuccinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.847 |
glyA | purD | Mmc1_0169 | Mmc1_3465 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | KEGG: pca:Pcar_2231 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.873 |