node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmc1_0002 | Mmc1_0726 | Mmc1_0002 | Mmc1_0726 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.670 |
Mmc1_0002 | Mmc1_2085 | Mmc1_0002 | Mmc1_2085 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.657 |
Mmc1_0002 | Mmc1_3488 | Mmc1_0002 | Mmc1_3488 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.657 |
Mmc1_0002 | Mmc1_3489 | Mmc1_0002 | Mmc1_3489 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.657 |
Mmc1_0002 | dut | Mmc1_0002 | Mmc1_3419 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.868 |
Mmc1_0002 | polA | Mmc1_0002 | Mmc1_3261 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.998 |
Mmc1_0111 | Mmc1_0726 | Mmc1_0111 | Mmc1_0726 | KEGG: rpd:RPD_3416 thiol-disulfide isomerase and thioredoxins. | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.745 |
Mmc1_0111 | Mmc1_2085 | Mmc1_0111 | Mmc1_2085 | KEGG: rpd:RPD_3416 thiol-disulfide isomerase and thioredoxins. | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.616 |
Mmc1_0111 | Mmc1_3488 | Mmc1_0111 | Mmc1_3488 | KEGG: rpd:RPD_3416 thiol-disulfide isomerase and thioredoxins. | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.616 |
Mmc1_0111 | Mmc1_3489 | Mmc1_0111 | Mmc1_3489 | KEGG: rpd:RPD_3416 thiol-disulfide isomerase and thioredoxins. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.616 |
Mmc1_0726 | Mmc1_0002 | Mmc1_0726 | Mmc1_0002 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.670 |
Mmc1_0726 | Mmc1_0111 | Mmc1_0726 | Mmc1_0111 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | KEGG: rpd:RPD_3416 thiol-disulfide isomerase and thioredoxins. | 0.745 |
Mmc1_0726 | Mmc1_1446 | Mmc1_0726 | Mmc1_1446 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | PFAM: band 7 protein; KEGG: ret:RHE_CH03557 putative membrane protease subunit protein. | 0.540 |
Mmc1_0726 | Mmc1_2085 | Mmc1_0726 | Mmc1_2085 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.950 |
Mmc1_0726 | Mmc1_3488 | Mmc1_0726 | Mmc1_3488 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | KEGG: mfa:Mfla_2542 hypothetical protein. | 0.950 |
Mmc1_0726 | Mmc1_3489 | Mmc1_0726 | Mmc1_3489 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.950 |
Mmc1_0726 | Mmc1_3503 | Mmc1_0726 | Mmc1_3503 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rme:Rmet_4055 periplasmic protein thiol. | 0.783 |
Mmc1_0726 | dut | Mmc1_0726 | Mmc1_3419 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.608 |
Mmc1_0726 | mpl | Mmc1_0726 | Mmc1_0725 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.799 |
Mmc1_0726 | polA | Mmc1_0726 | Mmc1_3261 | PFAM: protein of unknown function DUF179; KEGG: pha:PSHAa2600 hypothetical protein; Belongs to the UPF0301 (AlgH) family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.614 |